A T Hattersley Selected Research

Hepatocyte Nuclear Factors

1/2013	HNF1B deletions in patients with young-onset diabetes but no known renal disease.
1/2011	A role for coding functional variants in HNF4A in type 2 diabetes susceptibility.
5/2005	Molecular genetics and phenotypic characteristics of MODY caused by hepatocyte nuclear factor 4alpha mutations in a large European collection.
4/2005	Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1alpha mutation carriers.
9/2001	Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization.
2/2001	beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.
2/2001	beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations.
7/2000	Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1alpha gene mutations: evidence for pharmacogenetics in diabetes.
1/2000	Diagnosis of maturity-onset diabetes of the young in the pediatric diabetes clinic.

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A T Hattersley Research Topics

Disease

55	Type 2 Diabetes Mellitus (MODY) 01/2018 - 01/2000
16	Mason-Type Diabetes 10/2017 - 01/2000
15	Insulin Resistance 04/2010 - 08/2000
11	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2019 - 01/2000
9	Birth Weight (Birth Weights) 01/2018 - 01/2000
4	Gestational Diabetes (Gestational Diabetes Mellitus) 10/2017 - 02/2000
4	Cysts 01/2013 - 03/2000
3	Diabetes Mellitus 03/2011 - 09/2007
3	Type 3 Maturity-Onset Diabetes of the Young 04/2005 - 09/2000
2	Disease Progression 04/2009 - 05/2003
2	Fetal Growth Retardation (Intrauterine Growth Retardation) 11/2008 - 12/2006
2	Epilepsy (Aura) 05/2008 - 09/2007
2	Permanent Neonatal Diabetes Mellitus 05/2008 - 11/2007
2	Obesity 02/2006 - 12/2000
2	Glucose Intolerance 04/2005 - 01/2001
2	Hypersensitivity (Allergy) 04/2005 - 07/2000
2	Diabetic Nephropathies (Diabetic Nephropathy) 02/2005 - 04/2000
2	Renal cysts and diabetes syndrome 05/2004 - 01/2001
2	Cystic Kidney Diseases (Cystic Kidney Disease) 09/2001 - 03/2000
2	Hyperglycemia 07/2001 - 02/2001
1	Genetic Risk Score 12/2019
1	Seizures (Absence Seizure) 01/2017
1	Exocrine Pancreatic Insufficiency 05/2013
1	Congenital Hypothyroidism (Cretinism) 03/2011
1	Reinfection 03/2011
1	Hypothyroidism 03/2011
1	Liver Diseases (Liver Disease) 03/2011
1	Muscular Diseases (Myopathy) 02/2011
1	Insulinoma 10/2009
1	Autoimmune Diseases (Autoimmune Disease) 12/2008
1	Developmental Delay, Epilepsy, and Neonatal Diabetes 09/2007
1	Genetic Predisposition to Disease (Genetic Predisposition) 11/2006
1	Latent Autoimmune Diabetes in Adults 08/2006
1	Inflammation (Inflammations) 03/2006
1	Overweight 02/2006
1	Gout 01/2006
1	Atrophy 01/2006
1	Persistent Infection 02/2005
1	Amyloidosis 05/2003
1	Alzheimer Disease (Alzheimer's Disease) 05/2003
1	Cystic Fibrosis (Mucoviscidosis) 11/2002
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2002
1	Hypertension (High Blood Pressure) 09/2002

Drug/Important Bio-Agent (IBA)

33	Insulin (Novolin)FDA Link 01/2019 - 01/2000
16	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 02/2000
12	Transcription Factors (Transcription Factor)IBA 03/2011 - 01/2000
12	GlucokinaseIBA 11/2007 - 01/2000
12	Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA 11/2007 - 07/2000
9	Hepatocyte Nuclear FactorsIBA 01/2013 - 01/2000
7	Hepatocyte Nuclear Factor 1-betaIBA 12/2006 - 01/2000
5	AutoantibodiesIBA 12/2019 - 08/2006
4	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 12/2019 - 08/2006
4	AntibodiesIBA 12/2019 - 08/2006
4	C-PeptideIBA 01/2019 - 09/2011
4	CreatinineIBA 01/2012 - 03/2000
4	LipidsIBA 02/2011 - 08/2000
4	NFI Transcription FactorsIBA 04/2009 - 05/2004
3	Glyburide (Glibenclamide)FDA LinkGeneric 10/2017 - 04/2005
3	Adenosine Triphosphate (ATP)IBA 10/2017 - 09/2007
3	DNA (Deoxyribonucleic Acid)IBA 09/2007 - 04/2000
3	Mitochondrial DNA (mtDNA)IBA 07/2007 - 11/2005
3	Triglycerides (Triacylglycerol)IBA 11/2006 - 07/2001
2	PotassiumIBA 10/2017 - 09/2007
2	KATP ChannelsIBA 10/2017 - 11/2007
2	HDL CholesterolIBA 02/2013 - 11/2006
2	Proteins (Proteins, Gene)FDA Link 12/2008 - 04/2000
2	AlbuminsIBA 03/2006 - 02/2005
2	Indicators and Reagents (Reagents)IBA 02/2005 - 12/2001
2	Biological ProductsIBA 12/2004 - 09/2002
1	AntigensIBA 12/2019
1	Zinc Transporter 8IBA 12/2019
1	pancreatic and duodenal homeobox 1 proteinIBA 05/2013
1	Thyroglobulin FDA Link 03/2011
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 02/2011
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2010
1	Cytochrome P-450 CYP2C9IBA 01/2010
1	VitaminsIBA 10/2009
1	AntioxidantsIBA 10/2009
1	beta Carotene (Betacarotene)FDA Link 10/2009
1	Interleukin-18 (Interleukin 18)IBA 12/2008
1	Insulin-Like PeptidesIBA 11/2008
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2007
1	HLA-DQB1 antigen (HLA DQB1)IBA 01/2007
1	Metformin (Glucophage)FDA LinkGeneric 02/2006
1	Poly CIBA 11/2005
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2005
1	CytokinesIBA 10/2005
1	Apolipoprotein A-II (Apolipoprotein A2)IBA 05/2005
1	Tolbutamide (Orinase)FDA LinkGeneric 04/2005
1	3' Untranslated Regions (3' UTR)IBA 12/2004
1	Stearoyl-CoA DesaturaseIBA 12/2004
1	Amyloid (Amyloid Fibrils)IBA 05/2003
1	ApolipoproteinsIBA 05/2003
1	Apolipoproteins E (ApoE)IBA 05/2003
1	Pancreatic ExtractsIBA 05/2003
1	calpain 10IBA 06/2002
1	Protein Isoforms (Isoforms)IBA 04/2002

Therapy/Procedure

4	Therapeutics 07/2013 - 05/2003
1	Critical Care (Surgical Intensive Care) 01/2017
1	Ligation 01/2013